产品
编 号:F175418
分子式:C118H177N35O29S
分子量:2581.95
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
联系客服
产品详情
生物活性:
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat has encephalitogenic activity and induces T?cell proliferative. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat induces Th1 cytokine response as well as relatively high levels of IgG antibodies. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat produces a relapsing-remitting neurological disease with extensive plaque-like demyelination.

体内研究:
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat 可用于动物建模,构建小鼠脑脊髓炎模型。Animal Model:HLA-DR2 (DRB1*1501) mice
Dosage:200 μg (0.2 mL)
Administration:Intraperitoneal injection; once, for 38 days
Result:Resulted in paralysis of both hind and forelimbs.

体外研究:
Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55); 0-50 μg/mL; 72 h; lymph nodes cells) induces T?cell proliferative and secretes Th1 cytokines including IFN-γ, TNF-α, IL-10, IL-4 and IL-5. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat increases the level of IgG.
产品资料