产品
编 号：F173517
分子式：C8H8O3
分子量：152.15
分子式：C8H8O3
分子量：152.15
产品类型
规格
价格
是否有货
10g
100
In-stock
25g
160
In-stock
50g
256
In-stock
结构图
CAS No: 148-53-8
产品详情
生物活性：
o-Vanillin (2-Vanillin) is a nature product, could be extracted from Vanilla planifolia, Pinus koraiensis fruit. o-Vanillin is a potent antifungal agent. o-Vanillin inhibits the growth of mycelia by disrupting the integrity of cell walls and cell membranes. o-Vanillin inhibits Doxorubicin (HY-15142A)- and 4-hydroperoxycyclophosphamide-induced NF-κB activation.
体内研究：
o-Vanillin (2-Vanillin; 60 mg/kg; p.o.; daily, for 5 d) inhibits tumor growth in mice bearing A375 human melanoma xenografts.Animal Model:Male NSG mice with A375 human melanoma xenografts (12-16 weeks of age)
Dosage:60 mg/kg
Administration:Oral administration; daily, for 5 days
Result:Delayed the growth of A375 human melanoma xenografts in immunodeficient NSG mice.
体外研究：
o-Vanillin (2-Vanillin; 0-125 μg/mL; 24-72 h) inhibits the mycelial growth of A. flavus in a dose-dependent manner.o-Vanillin (0-100 μg/mL; 48 h; A. flavus) changes the morphology of mycelia and induces irregular shrinkage of the mycelia.o-Vanillin (0-100 μg/mL; A. flavus) decreases the protein content of the cell wall surface and the content of β-1,3-glucan.o-Vanillin (0-100 μg/mL; A. flavus) destroys cell membrane integrity. o-Vanillin releases cell constituents and decreases extracellular pH value.o-Vanillin (0-100 μg/mL) could effectively inhibit the growth of A. flavus on corn kernels.o-Vanillin (0-250 μM) inhibits doxorubicin-mediated induction of NF?B activity by 65% in A375/NF?B-Luc cells. o-Vanillin suppresses 4-HC-induced activity by 43%.
o-Vanillin (2-Vanillin) is a nature product, could be extracted from Vanilla planifolia, Pinus koraiensis fruit. o-Vanillin is a potent antifungal agent. o-Vanillin inhibits the growth of mycelia by disrupting the integrity of cell walls and cell membranes. o-Vanillin inhibits Doxorubicin (HY-15142A)- and 4-hydroperoxycyclophosphamide-induced NF-κB activation.
体内研究：
o-Vanillin (2-Vanillin; 60 mg/kg; p.o.; daily, for 5 d) inhibits tumor growth in mice bearing A375 human melanoma xenografts.Animal Model:Male NSG mice with A375 human melanoma xenografts (12-16 weeks of age)
Dosage:60 mg/kg
Administration:Oral administration; daily, for 5 days
Result:Delayed the growth of A375 human melanoma xenografts in immunodeficient NSG mice.
体外研究：
o-Vanillin (2-Vanillin; 0-125 μg/mL; 24-72 h) inhibits the mycelial growth of A. flavus in a dose-dependent manner.o-Vanillin (0-100 μg/mL; 48 h; A. flavus) changes the morphology of mycelia and induces irregular shrinkage of the mycelia.o-Vanillin (0-100 μg/mL; A. flavus) decreases the protein content of the cell wall surface and the content of β-1,3-glucan.o-Vanillin (0-100 μg/mL; A. flavus) destroys cell membrane integrity. o-Vanillin releases cell constituents and decreases extracellular pH value.o-Vanillin (0-100 μg/mL) could effectively inhibit the growth of A. flavus on corn kernels.o-Vanillin (0-250 μM) inhibits doxorubicin-mediated induction of NF?B activity by 65% in A375/NF?B-Luc cells. o-Vanillin suppresses 4-HC-induced activity by 43%.
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