产品
编 号:F172279
分子式:C23H32ClN5O9S2
分子量:622.11
产品类型
结构图
CAS No: 147816-24-8
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产品详情
生物活性:
Cefcapene pivoxil hydrochloride hydrate, the pivalate ester prodrug form of Cefcapene, is an orally active third-generation cephalosporin with a wide spectrum of anti-bacterial activity. Cefcapene pivoxil hydrochloride hydrate has the potential for the palmoplantar pustulosis (PPP) research.
体内研究:
Cefcapene pivoxil hydrochloride hydrate (oral administration; 100mg/kg; 4 days) is effective against invasive BLNAR strains in mice lung, it stimates peak antibiotic concentrations of 1 to 2 μg/ml in the blood of mice from 30 to 120 min after intragastric administration.Animal Model:Four-week-old female C57BL/6J mice with bacterial suspension in BSG (1×109 CFU)
Dosage:100 mg/kg
Administration:Oral administration; 100mg/kg; 4 days
Result:Was against H. influenzae colonization in mouse lung.