产品
编 号：F172213
分子式：C7H9NO6
分子量：203.15
分子式：C7H9NO6
分子量：203.15
产品类型
规格
价格
是否有货
1mg
询价
询价
结构图
CAS No: 147782-19-2
产品详情
生物活性：
DCG-IV is a potent agonist of group II mGluRs with EC50s of 0.35 and 0.09 μM for mGlu2R and mGlu3R, reapectively. DCG-IV is also a competitive antagonist at group I (IC50: mGlu1R/5R=389/630 μM) and III receptors (IC50: mGlu4R/6R/7R/8R= 22.5/39.6/40.1/32 μM). DCG-IV has anticonvulsive and neuroprotective effects.
体内研究：
DCG-IV (1-10 mg/kg; i.p.) depresses the phencyclidine (PCP)-induced hyperlocomotion.Animal Model:Male ICR mice weighing about 40 g (PCP-induced locomotor activity)
Dosage:10, 5, or 1 mg/kg
Administration:I.p.
Result:Reduced spontaneous activities of the animals at 10 or 5 mg/kg.
体外研究：
DCG-IV is also an NMDA receptor agonist in the rat cortical slice.
DCG-IV is a potent agonist of group II mGluRs with EC50s of 0.35 and 0.09 μM for mGlu2R and mGlu3R, reapectively. DCG-IV is also a competitive antagonist at group I (IC50: mGlu1R/5R=389/630 μM) and III receptors (IC50: mGlu4R/6R/7R/8R= 22.5/39.6/40.1/32 μM). DCG-IV has anticonvulsive and neuroprotective effects.
体内研究：
DCG-IV (1-10 mg/kg; i.p.) depresses the phencyclidine (PCP)-induced hyperlocomotion.Animal Model:Male ICR mice weighing about 40 g (PCP-induced locomotor activity)
Dosage:10, 5, or 1 mg/kg
Administration:I.p.
Result:Reduced spontaneous activities of the animals at 10 or 5 mg/kg.
体外研究：
DCG-IV is also an NMDA receptor agonist in the rat cortical slice.
产品资料
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