产品
编 号：F171963
分子式：C122H210N32O22
分子量：2477.17
分子式：C122H210N32O22
分子量：2477.17
产品类型
规格
价格
是否有货
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 147664-63-9
产品详情
生物活性：
Pexiganan (MSI 78 free base) is a synthetic analog of magainin 2. Pexiganan is a potent and orally active broad-spectrum antimicrobial peptide. Pexiganan can be used in the research of infections, such as diabetic foot ulcer infections.
体内研究：
Pexiganan (1, 3, 10 or 30 mg/kg, p.o., daily for three consecutive days) shows H. pylori clearance efficiency in H. pylori-infected mouse.Pexiganan (1 mg/kg, i.p.) shows antimicrobial activity in rat models of Gram-negative septic shock.Animal Model:H. pylori-infected mouse.
Dosage:1, 3, 10 or 30 mg/kg
Administration:Oral administration, daily for three consecutive days.
Result:Lowered H. pylori urease activities in mouse stomachs.
Animal Model:Rat models of Gram-negative septic shock (induced by E.coli ATCC 25922).
Dosage:1 mg/kg
Administration:Intraperitoneal injection (i.p.)
Result:Displayed antimicrobial activities and survival rates of 67.7%.
体外研究：
Pexiganan (MIC: 0-128 μg/mL approximately) shows broad-spectrum antibacterial activity against 3,109 clinical isolates of gram-positive and gram-negative, anaerobic and aerobic bacteria.Pexiganan (4 μg/mL) inhibits gastric ulcer strain and gastric cancer strain.
Pexiganan (MSI 78 free base) is a synthetic analog of magainin 2. Pexiganan is a potent and orally active broad-spectrum antimicrobial peptide. Pexiganan can be used in the research of infections, such as diabetic foot ulcer infections.
体内研究：
Pexiganan (1, 3, 10 or 30 mg/kg, p.o., daily for three consecutive days) shows H. pylori clearance efficiency in H. pylori-infected mouse.Pexiganan (1 mg/kg, i.p.) shows antimicrobial activity in rat models of Gram-negative septic shock.Animal Model:H. pylori-infected mouse.
Dosage:1, 3, 10 or 30 mg/kg
Administration:Oral administration, daily for three consecutive days.
Result:Lowered H. pylori urease activities in mouse stomachs.
Animal Model:Rat models of Gram-negative septic shock (induced by E.coli ATCC 25922).
Dosage:1 mg/kg
Administration:Intraperitoneal injection (i.p.)
Result:Displayed antimicrobial activities and survival rates of 67.7%.
体外研究：
Pexiganan (MIC: 0-128 μg/mL approximately) shows broad-spectrum antibacterial activity against 3,109 clinical isolates of gram-positive and gram-negative, anaerobic and aerobic bacteria.Pexiganan (4 μg/mL) inhibits gastric ulcer strain and gastric cancer strain.
产品资料
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