产品
编 号:F171777
分子式:C21H16O4
分子量:332.35
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10mM*1mL in DMSO
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5mg
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10mg
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25mg
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50mg
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100mg
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生物活性:
DiMNF (3',4'-Dimethoxy-αNF) is a selective aryl hydrocarbon receptor (AHR) modulator. DiMNF is a competitive AHR ligand (IC50 = 21 nM) with apparent antagonistic activity. DiMNF can be used as an anti-inflammatory agent.

体外研究:
DiMNF (3',4'-Dimethoxy-αNF) (10 μM; 4 h) minimally influences AHR gene battery.DiMNF (10 μM; 1 h) effectively suppresses cytokine-mediated inflammatory gene expression.DiMNF adopts a unique orientation within the ligand binding pocket of AHR.
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