产品
编 号：F171724
分子式：C22H18BrN3O2
分子量：436.3
分子式：C22H18BrN3O2
分子量：436.3
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价格
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CAS No: 147523-65-7
产品详情
生物活性：
LY288513 is a selective non-peptide CCK-B receptor antagonist with an IC50 value of 16 nM. LY288513 produces an anxiolytic-like action in mice.
体内研究：
LY288513 (3, 10 mg/kg, i.p.; 10, 30 mg/kg, p.o.) produces an anxiolytic-like action in mice.LY288513 (1000 mg/kg, p.o.) potentiates the effects of a CNS depressant, slightly lowered body temperature, and had modest sedative effects only at the highest dose examined.Animal Model:Male CD-l mice
Dosage:3, 10 mg/kg; 10, 30 mg/kg
Administration:I.p.; p.o.
Result:Displayed anxiolytic-like effects in the elevated plusmaze.
体外研究：
LY288513 (10 nM; 2 days) suppresses the effects of CCK-8 on CD4+ T cell subset-specific transcription factors.
LY288513 is a selective non-peptide CCK-B receptor antagonist with an IC50 value of 16 nM. LY288513 produces an anxiolytic-like action in mice.
体内研究：
LY288513 (3, 10 mg/kg, i.p.; 10, 30 mg/kg, p.o.) produces an anxiolytic-like action in mice.LY288513 (1000 mg/kg, p.o.) potentiates the effects of a CNS depressant, slightly lowered body temperature, and had modest sedative effects only at the highest dose examined.Animal Model:Male CD-l mice
Dosage:3, 10 mg/kg; 10, 30 mg/kg
Administration:I.p.; p.o.
Result:Displayed anxiolytic-like effects in the elevated plusmaze.
体外研究：
LY288513 (10 nM; 2 days) suppresses the effects of CCK-8 on CD4+ T cell subset-specific transcription factors.
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