产品
编 号:F171222
分子式:C19H23NO
分子量:281.39
产品类型
结构图
CAS No: 147-20-6
联系客服
产品详情
生物活性:
Diphenylpyraline is a potent histamine H1?receptor antagonist. Diphenylpyraline acts as an orally active antihistamine agent?with antimuscarinic and antiallergic effects. Diphenylpyraline can be used for the research of allergic diseases, including rhinitis and hay fever, and pruritic skin disorders et.al.
体内研究:
Diphenylpyraline (intraperitoneal?injection; 5-10 mg/kg) elevates extracellular dopamine levels (~200%) in mouse nucleus accumbens and induces locomotor activation in mice.Animal Model:C57BL/6 mice
Dosage:5-10 mg/kg
Administration:Intraperitoneal?injection
Result:Had psychostimulant properties.
体外研究:
Diphenylpyraline (10 μM) markedly inhibits dopamine uptakein mouse nucleus accumbens slices.