产品
编 号：F171164
分子式：C45H58N10O9S2
分子量：947.13
分子式：C45H58N10O9S2
分子量：947.13
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
25mg
询价
询价
结构图
CAS No: 147159-51-1
产品详情
生物活性：
TT-232 (CAP-232), a somatostatin derivative, is a peptide SSTR1/SSTR4 agonist. TT-232 inhibits cancer cell proliferation and induces apoptosis. TT-232 is also a broad-spectrum anti-inflammatory and analgesic agent.
体内研究：
TT-232 (15-750 μg/kg/day, twice a day) inhibits tumor growth in mice transplanted with Colon 26 cell.TT-232 (0.6 or 15 μg/kg s.c or i.p.) shows antitumor effect on P-388 rodent lymphocytic leukemia tumor mice.TT-232 (7.5-20 μg/kg, i.v.) inhibits Carrageenin-induced paw oedema in rats.Animal Model:Mice transplanted with Colon 26 cell .
Dosage:15, 150, 750 μg/kg/day
Administration:Intraperitoneal injection (i.p.)
Result:Reached 70% tumor inhibition at 750 μg/kg.
体外研究：
TT-232 (10 μg/mL, 48 h) induces apoptosis in human colon (HT-29 and SW620), pancreatic (818), leukemia (K-562), melanoma (WM 938/B, M-1 and EP) and lymphoma (HT-58) tumor cell lines.TT-232 (20-30 μg/mL, 24 h) shows antiproliferative effect on various human tumor cell lines.
TT-232 (CAP-232), a somatostatin derivative, is a peptide SSTR1/SSTR4 agonist. TT-232 inhibits cancer cell proliferation and induces apoptosis. TT-232 is also a broad-spectrum anti-inflammatory and analgesic agent.
体内研究：
TT-232 (15-750 μg/kg/day, twice a day) inhibits tumor growth in mice transplanted with Colon 26 cell.TT-232 (0.6 or 15 μg/kg s.c or i.p.) shows antitumor effect on P-388 rodent lymphocytic leukemia tumor mice.TT-232 (7.5-20 μg/kg, i.v.) inhibits Carrageenin-induced paw oedema in rats.Animal Model:Mice transplanted with Colon 26 cell .
Dosage:15, 150, 750 μg/kg/day
Administration:Intraperitoneal injection (i.p.)
Result:Reached 70% tumor inhibition at 750 μg/kg.
体外研究：
TT-232 (10 μg/mL, 48 h) induces apoptosis in human colon (HT-29 and SW620), pancreatic (818), leukemia (K-562), melanoma (WM 938/B, M-1 and EP) and lymphoma (HT-58) tumor cell lines.TT-232 (20-30 μg/mL, 24 h) shows antiproliferative effect on various human tumor cell lines.
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